Protein Name 5-hydroxytryptamine receptor 3A
Organism Rattus norvegicus
Gene ID 79246
Gene Symbol

Htr3a

UniProt P35563 (5HT3A_RAT), Q62999 (Q62999_RAT)
Relationships Total Number of functionally related compound(s) : 384
Total Number of Articles : 671
Description

5-hydroxytryptamine receptor 3A

Gene Summary

Enables serotonin-gated cation-selective channel activity. Involved in several processes, including positive regulation of ion transmembrane transporter activity; response to cocaine; and response to ethanol. Located in several cellular components, including axon; neuronal cell body; and plasma membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Orthologous to human HTR3A (5-hydroxytryptamine receptor 3A). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 5-hydroxytryptamine receptor 3A
  • 5-HT-3
  • 5-HT3 receptor
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Properties