Title : Role of formation of an ERK-FAK-paxillin complex in migration of human corneal epithelial cells during wound closure in vitro.

Pub. Date : 2009 Dec

PMID : 19494198






2 Functional Relationships(s)
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1 Wounding increased the phosphorylation of ERK as well as the tyrosine phosphorylation of FAK and paxillin in a manner sensitive to PD98059. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one protein tyrosine kinase 2 Homo sapiens
2 Furthermore, wounding induced the formation of an ERK-FAK-paxillin complex and this effect as well as the wounding-induced formation of focal adhesions, membrane ruffles, and bundles of F-actin, were inhibited by PD98059. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one protein tyrosine kinase 2 Homo sapiens