Title : Modulation of androgen and estrogen receptor expression by antiepileptic drugs and steroids in hippocampus of patients with temporal lobe epilepsy.

Pub. Date : 2009 Aug

PMID : 19490052






1 Functional Relationships(s)
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1 RESULTS: In both, humans and cell lines, the expression of testosterone metabolising CYP3A4 (human) or CYP3A11 (mouse) and AR was up-regulated when P450-inducing AEDs and/or prednisolone had been applied. Prednisolone cytochrome P450 family 3 subfamily A member 4 Homo sapiens