Title : Oncogenic Flt3 receptors display different specificity and kinetics of autophosphorylation.

Pub. Date : 2009 Aug

PMID : 19477218






3 Functional Relationships(s)
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1 By the use of a panel of phosphospecific antibodies directed against potential tyrosine phosphorylation sites in Flt3, we identified several novel phosphorylation sites in Flt3 and studied the kinetics and specificity of ligand-induced phosphorylation in living cells. Tyrosine fms related receptor tyrosine kinase 3 Homo sapiens
2 By the use of a panel of phosphospecific antibodies directed against potential tyrosine phosphorylation sites in Flt3, we identified several novel phosphorylation sites in Flt3 and studied the kinetics and specificity of ligand-induced phosphorylation in living cells. Tyrosine fms related receptor tyrosine kinase 3 Homo sapiens
3 Furthermore, we show that tyrosines 726, 793, and 842 are novel phosphorylation sites of Flt3 in intact cells. Tyrosine fms related receptor tyrosine kinase 3 Homo sapiens