Title : Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: I. The role of arsenolysis.

Pub. Date : 2009 Aug

PMID : 19474219






2 Functional Relationships(s)
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1 Furthermore, the relative capacity of thiols to support AsV reduction mediated by PNP, GPa, PTA, and GAPDH apparently depended on the type of arsenylated metabolites (i.e., arsenate ester or anhydride) produced by these enzymes. Sulfhydryl Compounds glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
2 Importantly, AsV reduction by both acetyl-arsenate-producing enzymes (i.e., PTA and GAPDH) exhibited striking similarities in responsiveness to various thiols, thus highlighting the role of arsenylated metabolite formation. Sulfhydryl Compounds glyceraldehyde-3-phosphate dehydrogenase Homo sapiens