Title : Photonucleophilic addition of the epsilon-amino group of lysine to a triflusal metabolite as a mechanistic key to photoallergy mediated by the parent drug.

Pub. Date : 2009 Jul

PMID : 19462393






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A mechanism for triflusal-induced photoallergy involving complexation of 2-hydroxy-4-trifluoromethylbenzoic acid with site I of human serum albumin and subsequent formation of a covalent adduct by photoreaction between a metabolite and a neighboring lysine residue is proposed. 4-trifluoromethylsalicylic acid albumin Homo sapiens