Title : Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice.

Pub. Date : 2009 Jul

PMID : 19461019






2 Functional Relationships(s)
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1 Although both dosages of Ac-YVAD-CMK attenuated the mature IL-1beta induction, only high-dose treatment group significantly inhibited the phosphorylation of JNK, MMP-9 induction, and ZO-1 degradation. ac-yvad chemokine (C-X-C motif) ligand 9 Mus musculus
2 The neurovascular protection of Ac-YVAD-CMK may be provided by the inhibition of JNK-mediated MMP-9 induction and the consequent preservation of tight junction protein ZO-1. ac-yvad chemokine (C-X-C motif) ligand 9 Mus musculus