Title : Adrenergic regulation of the rapid component of delayed rectifier K+ current: implications for arrhythmogenesis in LQT2 patients.

Pub. Date : 2009 Jul

PMID : 19419905






1 Functional Relationships(s)
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1 RESULTS: In HL-1 cardiomyocytes expressing human alpha(1A)-adrenoceptor, superfusion with phenylephrine significantly reduced I(Kr) amplitude, shifted current activation to more positive potentials, and accelerated kinetics of deactivation. Phenylephrine adrenoceptor alpha 1A Homo sapiens