| Protein Name | adrenoceptor alpha 1A |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 148 |
| Gene Symbol | ADRA1A |
| UniProt | P35348 (ADA1A_HUMAN), B0ZBD3 (B0ZBD3_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
129
Total Number of Articles : 153 |
Description |
adrenoceptor alpha 1A |
| Gene Summary |
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008] |
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