Title : Foxa2-dependent hepatic gene regulatory networks depend on physiological state.

Pub. Date : 2009 Jul 9

PMID : 19417011






3 Functional Relationships(s)
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1 The winged helix transcription factor Foxa2 is required to prevent intrahepatic cholestasis and liver injury in mice fed a cholic acid-enriched diet. Cholic Acid forkhead box A2 Mus musculus
2 Here, we use functional genomics to study how Foxa2 regulates its targets in a cholic acid-dependent manner. Cholic Acid forkhead box A2 Mus musculus
3 We also discovered distinct feed-forward regulatory loops controlling Foxa2-dependent targets in a cholic acid-dependent or -independent manner. Cholic Acid forkhead box A2 Mus musculus