Title : Lysine-based peptide-functionalized PLGA foams for controlled DNA delivery.

Pub. Date : 2009 Aug 19

PMID : 19409431






1 Functional Relationships(s)
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1 Tailor-designed l-lysine peptides (K4 and K20) were employed to modify the surface charge of PLGA foams using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide and N-hydroxysuccinimide cross linkers and the effects of charge modification of PLGA were examined in three main aspects: DNA adsorption, DNA release properties and DNA transfection. Lysine keratin 20 Homo sapiens