Pub. Date : 2009
PMID : 19404564
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma. | gadolinium ethoxybenzyl DTPA | solute carrier organic anion transporter family member 1B3 | Homo sapiens |
| 2 | HCCs with Gd-EOB-DTPA uptake overexpressed OATP1B3 compared with HCCs without Gd-EOB-DTPA uptake, and OATP1B3 levels were significantly correlated with ERs (r=0.91, P<0.0001). | gadolinium ethoxybenzyl DTPA | solute carrier organic anion transporter family member 1B3 | Homo sapiens |
| 3 | HCCs with Gd-EOB-DTPA uptake overexpressed OATP1B3 compared with HCCs without Gd-EOB-DTPA uptake, and OATP1B3 levels were significantly correlated with ERs (r=0.91, P<0.0001). | gadolinium ethoxybenzyl DTPA | solute carrier organic anion transporter family member 1B3 | Homo sapiens |
| 4 | CONCLUSIONS: Uptake of Gd-EOB-DTPA in HCC is determined by expression of OATP1B3 rather than by tumor differentiation or bile production. | gadolinium ethoxybenzyl DTPA | solute carrier organic anion transporter family member 1B3 | Homo sapiens |