Title : The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans.

Pub. Date : 1991 Oct 25

PMID : 1939083






1 Functional Relationships(s)
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Protein Name
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1 The N-terminal portion of HCII contains two acidic repeats (Glu56-Asp-Asp-Asp-Tyr-Leu-Asp and Glu69-Asp-Asp-Asp-Tyr-Ile-Asp) that may bind to anion-binding exosite I of thrombin to facilitate covalent complex formation. Tyr-Ile-Asp serpin family D member 1 Homo sapiens