Title : Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer's disease mouse.

Pub. Date : 2009 Jan

PMID : 19384583






3 Functional Relationships(s)
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1 Polyphenols extracted from grape seeds are able to inhibit amyloid-beta (Abeta) aggregation, reduce Abeta production and protect against Abeta neurotoxicity in vitro. Polyphenols amyloid beta (A4) precursor protein Mus musculus
2 Polyphenols extracted from grape seeds are able to inhibit amyloid-beta (Abeta) aggregation, reduce Abeta production and protect against Abeta neurotoxicity in vitro. Polyphenols amyloid beta (A4) precursor protein Mus musculus
3 Conclusively, polyphenol-rich GSE prevents the Abeta deposition and attenuates the inflammation in the brain of a transgenic mouse model, and this thus is promising in delaying development of AD. Polyphenols amyloid beta (A4) precursor protein Mus musculus