Title : Analgesic effect of milnacipran is associated with c-Fos expression in the anterior cingulate cortex in the rat neuropathic pain model.

Pub. Date : 2009 Aug

PMID : 19383518






3 Functional Relationships(s)
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1 Analgesic effect of milnacipran is associated with c-Fos expression in the anterior cingulate cortex in the rat neuropathic pain model. Milnacipran Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 The increased level of c-Fos expression in the anterior cingulate cortex (ACC) induced by noxious mechanical stimulation was significantly inhibited by the continuous administration of milnacipran, indicating that milnacipran might cause a functional modification in the nociceptive processing in the ACC. Milnacipran Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 The increased level of c-Fos expression in the anterior cingulate cortex (ACC) induced by noxious mechanical stimulation was significantly inhibited by the continuous administration of milnacipran, indicating that milnacipran might cause a functional modification in the nociceptive processing in the ACC. Milnacipran Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus