Pub. Date : 2009 Jun
PMID : 19359419
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins. | Heparin | stabilin 2 | Homo sapiens |
2 | Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins. | Heparin | stabilin 2 | Homo sapiens |
3 | The human hyaluronic acid (HA) receptor for endocytosis (HARE/stabilin-2) is the primary clearance receptor for systemic HA, chondroitin sulfates, and heparin, but not for heparan sulfate or keratan sulfate (Harris EN, Weigel JA, Weigel PH. | Heparin | stabilin 2 | Homo sapiens |
4 | The human hyaluronic acid (HA) receptor for endocytosis (HARE/stabilin-2) is the primary clearance receptor for systemic HA, chondroitin sulfates, and heparin, but not for heparan sulfate or keratan sulfate (Harris EN, Weigel JA, Weigel PH. | Heparin | stabilin 2 | Homo sapiens |
5 | In this study, we demonstrate that anti-HARE antibodies specifically block the uptake of LMWH and UFH by isolated rat liver SECs and by human 293 cells expressing recombinant human HARE (hHARE). | Heparin | stabilin 2 | Homo sapiens |
6 | We conclude that both UFH and LMWH are cleared by HARE/Stab2 and that the differences in the affinities of HARE binding to LMWH and UFH likely explain the longer in vivo circulating half-life of LMWH compared with UFH. | Heparin | stabilin 2 | Homo sapiens |
7 | We conclude that both UFH and LMWH are cleared by HARE/Stab2 and that the differences in the affinities of HARE binding to LMWH and UFH likely explain the longer in vivo circulating half-life of LMWH compared with UFH. | Heparin | stabilin 2 | Homo sapiens |
8 | We conclude that both UFH and LMWH are cleared by HARE/Stab2 and that the differences in the affinities of HARE binding to LMWH and UFH likely explain the longer in vivo circulating half-life of LMWH compared with UFH. | Heparin | stabilin 2 | Homo sapiens |
9 | We conclude that both UFH and LMWH are cleared by HARE/Stab2 and that the differences in the affinities of HARE binding to LMWH and UFH likely explain the longer in vivo circulating half-life of LMWH compared with UFH. | Heparin | stabilin 2 | Homo sapiens |
10 | We conclude that both UFH and LMWH are cleared by HARE/Stab2 and that the differences in the affinities of HARE binding to LMWH and UFH likely explain the longer in vivo circulating half-life of LMWH compared with UFH. | Heparin | stabilin 2 | Homo sapiens |