Protein Name stabilin 2
Organism Homo sapiens
Gene ID 55576
Gene Symbol

STAB2

UniProt Q8WWQ8 (STAB2_HUMAN)
Relationships Total Number of functionally related compound(s) : 97
Total Number of Articles : 54
Description

stabilin 2

Gene Summary

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]

synonyms
  • stabilin-2
  • CD44-like precursor FELL
  • FAS1 EGF-like and X-link domain containing adhesion molecule-2
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Properties