Pub. Date : 2009 Jun
PMID : 19357830
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Serine-385 phosphorylation of inwardly rectifying K+ channel subunit (Kir6.2) by AMP-dependent protein kinase plays a key role in rosiglitazone-induced closure of the K(ATP) channel and insulin secretion in rats. | Serine | potassium inwardly-rectifying channel, subfamily J, member 11 | Rattus norvegicus |
2 | The serine residue at amino acid position 385 of Kir6.2 was found to be the substrate phosphorylation site of AMPK when activated by rosiglitazone or AICAR. | Serine | potassium inwardly-rectifying channel, subfamily J, member 11 | Rattus norvegicus |
3 | Phosphorylation of the Ser(385) residue of the Kir6.2 subunit of the K(ATP) channel by AMPK may play a role in insulin secretion. | Serine | potassium inwardly-rectifying channel, subfamily J, member 11 | Rattus norvegicus |