Pub. Date : 2008 Dec
PMID : 19356098
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of human UGT1A1 by bilirubin through AhR dependent pathway. | Bilirubin | aryl hydrocarbon receptor | Homo sapiens |
| 2 | In this report, we show findings of the induction of the reporter gene (-3475/+14) of UGT1A1 in HepG2 cells by bilirubin at 50 microM, 100 microM, with human aryl hydrocarbon receptor (hAhR). | Bilirubin | aryl hydrocarbon receptor | Homo sapiens |
| 3 | In this report, we show findings of the induction of the reporter gene (-3475/+14) of UGT1A1 in HepG2 cells by bilirubin at 50 microM, 100 microM, with human aryl hydrocarbon receptor (hAhR). | Bilirubin | aryl hydrocarbon receptor | Homo sapiens |
| 4 | These results indicate that the induction of UGT1A1 by bilirubin-AhR did not depend on the elevation of AhR but on ligand binding. | Bilirubin | aryl hydrocarbon receptor | Homo sapiens |
| 5 | This is the first report showing direct induction of UGT1A1 by a bilirubin through AhR pathway. | Bilirubin | aryl hydrocarbon receptor | Homo sapiens |