Title : PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells.

Pub. Date : 2009 Jan

PMID : 19343001






2 Functional Relationships(s)
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1 It should be noted that bufalin transiently activated the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway and then inhibited it completely, and upregulated the Casitas B-lineage lymphoma (Cbl) family of ubiquitin ligases, upstream modulators of PI3K. bufalin Cbl proto-oncogene Homo sapiens
2 It should be noted that bufalin transiently activated the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway and then inhibited it completely, and upregulated the Casitas B-lineage lymphoma (Cbl) family of ubiquitin ligases, upstream modulators of PI3K. bufalin Cbl proto-oncogene Homo sapiens