Title : Down-regulation of cdc2 in senescent human and hamster cells.

Pub. Date : 1991 Nov 1

PMID : 1933864






1 Functional Relationships(s)
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1 In contrast to senescent and low serum-arrested cells, cdc2 mRNA was expressed at normal levels in cells partially growth arrested by isoleucine deficiency in G1, by aphidicolin at G1-S, by etoposide in G2, or by Colcemid in the M phase of the cell cycle, indicating that cdc2 down-regulation does not always occur upon growth arrest. Aphidicolin cyclin dependent kinase 1 Homo sapiens