Title : Targeting receptor tyrosine kinases for chemoprevention by green tea catechin, EGCG.

Pub. Date : 2008 Jun

PMID : 19325845






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 EGCG inhibits the activation of EGFR (erbB1), HER2 (neu/erbB2) and also HER3 (neu/erbB3), which belong to subclass I of the RTK superfamily, in various types of human cancer cells. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
2 EGCG inhibits the activation of EGFR (erbB1), HER2 (neu/erbB2) and also HER3 (neu/erbB3), which belong to subclass I of the RTK superfamily, in various types of human cancer cells. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
3 In addition, EGCG alters membrane lipid organization and thus inhibits the dimerization and activation of EGFR. epigallocatechin gallate epidermal growth factor receptor Homo sapiens