Title : FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro.

Pub. Date : 2009 Apr 1

PMID : 19318574






2 Functional Relationships(s)
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1 Using a cell-based screening approach, we generated FLT3-internal tandem duplication (ITD)-expressing cell lines resistant to the FLT3 inhibitors SU5614, PKC412, and sorafenib. SU 5614 fms related receptor tyrosine kinase 3 Homo sapiens
2 Using a cell-based screening approach, we generated FLT3-internal tandem duplication (ITD)-expressing cell lines resistant to the FLT3 inhibitors SU5614, PKC412, and sorafenib. SU 5614 fms related receptor tyrosine kinase 3 Homo sapiens