Title : HMGB1/2 can target DNA for illegitimate cleavage by the RAG1/2 complex.

Pub. Date : 2009 Mar 24

PMID : 19317908






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The high mobility group proteins HMGB1 and HMGB2 (HMGB1/2) are highly abundant architectural DNA binding proteins known to promote RAG-mediated synapsis and cleavage of consensus recombination signals in vitro by facilitating RSS binding and bending by the RAG1/2 complex. RSS high mobility group box 1 Homo sapiens