Title : XRCC1 interacts with the p58 subunit of DNA Pol alpha-primase and may coordinate DNA repair and replication during S phase.

Pub. Date : 2009 Jun

PMID : 19305001






1 Functional Relationships(s)
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1 Overexpression of the XRCC1-BRCT1 domain in HeLa cells induces poly(ADP-ribose) synthesis, PARP-1 and XRCC1-BRCT1 poly(ADP-ribosyl)ation and a strong S phase delay in the presence of DNA damage. Poly Adenosine Diphosphate Ribose X-ray repair cross complementing 1 Homo sapiens