Pub. Date : 2009 Jun
PMID : 19299526
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions. | Thiabendazole | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |
| 2 | Thiabendazole (TBZ) and its major metabolite 5-hydroxythiabendazole (5OH-TBZ) were screened for potential time-dependent inhibition (TDI) against CYP1A2. | Thiabendazole | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |
| 3 | Thiabendazole (TBZ) and its major metabolite 5-hydroxythiabendazole (5OH-TBZ) were screened for potential time-dependent inhibition (TDI) against CYP1A2. | Thiabendazole | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |
| 4 | IC(50) shift studies also demonstrated that TBZ was a TDI of CYP1A2. | Thiabendazole | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |