Title : The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.

Pub. Date : 2009 May

PMID : 19292763






1 Functional Relationships(s)
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1 We identified a human leucocyte antigen-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain (A1-13), dependent upon generation of a vicinal disulphide bond between adjacent cysteines (A6-A7). disulphide insulin Homo sapiens