Title : IGF-I and its variant, des-(1-3)IGF-I, enhance growth in rats with reduced renal mass.

Pub. Date : 1991 Oct

PMID : 1928375






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1 Body weight gain, food utilization, and nitrogen balance during the treatment period were significantly increased in rats treated with IGF-I at both the lower and higher doses and in those treated with des-(1-3)IGF-I. Diethylstilbestrol insulin-like growth factor 1 Rattus norvegicus
2 The improved nitrogen balance in the des-(1-3)IGF-I group could at least partly be explained by a diminished rate of muscle protein breakdown, as indicated by the reduced urinary excretion rate of 3-methylhistidine. Diethylstilbestrol insulin-like growth factor 1 Rattus norvegicus