Title : Aurora A regulates prometaphase progression by inhibiting the ability of RASSF1A to suppress APC-Cdc20 activity.

Pub. Date : 2009 Mar 15

PMID : 19276349






2 Functional Relationships(s)
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1 Here, we show that Aurora A and B associate with and phosphorylate RASSF1A on serine 203 in vivo at different times and in different subcellular compartments during mitosis. Serine Ras association domain family member 1 Homo sapiens
2 Finally, RASSF1A phosphorylation on serine 203 was up-regulated in Aurora A-overexpressing human tumors. Serine Ras association domain family member 1 Homo sapiens