Title : Selective, potent PPARgamma agonists with cyclopentenone core structure.

Pub. Date : 2009 Apr 1

PMID : 19275963






1 Functional Relationships(s)
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1 A series of analogues of the PPARgamma ligand 15-deoxy-Delta(12,14)-PGJ(2) have been synthesized by functionalization of a 5-alkyl-4-hydroxycyclopentenone core structure obtained by Piancatelli rearrangement of precursor furylcarbinol. 15-deoxy-delta peroxisome proliferator activated receptor gamma Homo sapiens