Pub. Date : 2009 Mar 16
PMID : 19273625
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In human purified naive T cells, PGE2 acts via prostaglandin receptor EP2- and EP4-mediated signaling and cyclic AMP pathways to up-regulate IL-23 and IL-1 receptor expression. | Dinoprostone | interleukin 23 subunit alpha | Homo sapiens |
| 2 | These findings, together with the altered IL-12/IL-23 balance induced by PGE2 in dendritic cells, further highlight the crucial role of the inflammatory microenvironment in Th17 cell development and regulation. | Dinoprostone | interleukin 23 subunit alpha | Homo sapiens |