Pub. Date : 2007 Sep
PMID : 19262706
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the experimental studies, S-1 plus irinotecan showed augmented antitumor activity against tumors with high TS activity (P < .01) compared with either agent alone. | Irinotecan | thymidylate synthetase | Homo sapiens |
| 2 | A potential mechanism for this effect was suggested by the significant reduction in TS activity observed following irinotecan administration in tumors with high TS activity. | Irinotecan | thymidylate synthetase | Homo sapiens |
| 3 | A potential mechanism for this effect was suggested by the significant reduction in TS activity observed following irinotecan administration in tumors with high TS activity. | Irinotecan | thymidylate synthetase | Homo sapiens |
| 4 | CONCLUSION: This study suggests that, via down-regulation of TS by irinotecan treatment, combination chemotherapy with S-1 and irinotecan could be effective in gastric cancer patients with high TS levels. | Irinotecan | thymidylate synthetase | Homo sapiens |
| 5 | CONCLUSION: This study suggests that, via down-regulation of TS by irinotecan treatment, combination chemotherapy with S-1 and irinotecan could be effective in gastric cancer patients with high TS levels. | Irinotecan | thymidylate synthetase | Homo sapiens |
| 6 | CONCLUSION: This study suggests that, via down-regulation of TS by irinotecan treatment, combination chemotherapy with S-1 and irinotecan could be effective in gastric cancer patients with high TS levels. | Irinotecan | thymidylate synthetase | Homo sapiens |
| 7 | CONCLUSION: This study suggests that, via down-regulation of TS by irinotecan treatment, combination chemotherapy with S-1 and irinotecan could be effective in gastric cancer patients with high TS levels. | Irinotecan | thymidylate synthetase | Homo sapiens |