Title : The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts.

Pub. Date : 2009 May 1

PMID : 19259985






1 Functional Relationships(s)
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Protein Name
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1 Runx2 increases expression of the glycosyltransferase Exostosin-1 (Ext1) and heparanase, as well as alters the relative expression of N-linked sulfotransferases (Ndst1 = Ndst2 > Ndst3) and enzymes mediating O-linked sulfation of heparan sulfate (Hs2st > Hs6st) or chondroitin sulfate (Cs4st > Cs6st). Heparitin Sulfate N-deacetylase and N-sulfotransferase 1 Homo sapiens