Title : Pyrethroid insecticides: isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor.

Pub. Date : 2009 May 15

PMID : 19249324






2 Functional Relationships(s)
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1 The aim of this study was to determine whether pyrethroids induce carboxylesterases and CYP3A4, and whether the induction is correlated inversely with their hydrolysis. Pyrethrins carboxylesterase 1 Homo sapiens
2 Some pyrethroids such as bioresmethrin were preferably hydrolyzed by carboxylesterase HCE1, whereas others such as bifenthrin preferably by HCE2. Pyrethrins carboxylesterase 1 Homo sapiens