Pub. Date : 2009 Mar
PMID : 19247191
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibitory effect of ghrelin on nicotine-induced VCAM-1 expression in human umbilical vein endothelial cells. | Nicotine | vascular cell adhesion molecule 1 | Homo sapiens |
| 2 | However, it is unknown how ghrelin regulates nicotine-induced vascular cell adhesion molecule-1 (VCAM-1) expression. | Nicotine | vascular cell adhesion molecule 1 | Homo sapiens |
| 3 | However, it is unknown how ghrelin regulates nicotine-induced vascular cell adhesion molecule-1 (VCAM-1) expression. | Nicotine | vascular cell adhesion molecule 1 | Homo sapiens |
| 4 | We examined nicotine-induced VCAM-1 expression in human umbilical vein endothelial cells pretreated with ghrelin and detected the activity of protein kinase C (PKC), p38 mitogen-activated protein kinase (p38 MAPK), and nuclear factor (NF)-kappaB. | Nicotine | vascular cell adhesion molecule 1 | Homo sapiens |
| 5 | Our study showed that ghrelin inhibited nicotine-induced VCAM-1 expression in human umbilical vein endothelial cells in a concentration-dependent and time-dependent way. | Nicotine | vascular cell adhesion molecule 1 | Homo sapiens |
| 6 | The results suggest that ghrelin inhibits nicotine-induced VCAM-1 expression, and PKC, p38 MAPK, and NF-kappaB play active roles in that process. | Nicotine | vascular cell adhesion molecule 1 | Homo sapiens |