Pub. Date : 2009 Mar
PMID : 19223575
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The AhR ligand 3,3"-diindolylmethane (DIM) is a beneficial dietary constituent that prevents breast tumors in rodents and is associated with decreased breast cancer risk in humans. | 3,3'-diindolylmethane | aryl hydrocarbon receptor | Homo sapiens |
| 2 | We find that DIM and TCDD have differing abilities to activate the distinct AhR-controlled pathways. | 3,3'-diindolylmethane | aryl hydrocarbon receptor | Homo sapiens |
| 3 | Our findings reveal that DIM and TCDD each elicit a unique pattern of change in pathways that control estrogen action; such patterns may determine if an AhR ligand has beneficial or adverse health effects. | 3,3'-diindolylmethane | aryl hydrocarbon receptor | Homo sapiens |