Title : cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation.

Pub. Date : 2009 Mar 1

PMID : 19223549






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 This XIAP-dependent event occurs in response to camptotechin or etoposide/VP16; however, XIAP is dispensable for activation of NF-kappaB by doxorubicin, which engages a MEK-ERK pathway to activate IKK. Etoposide X-linked inhibitor of apoptosis Homo sapiens
2 This XIAP-dependent event occurs in response to camptotechin or etoposide/VP16; however, XIAP is dispensable for activation of NF-kappaB by doxorubicin, which engages a MEK-ERK pathway to activate IKK. Etoposide X-linked inhibitor of apoptosis Homo sapiens