Title : Melatonin inhibits LPS-induced NO production in rat endothelial cells.

Pub. Date : 2009 Apr

PMID : 19215575






1 Functional Relationships(s)
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1 We have previously shown that melatonin, in the nanomolar range, inhibits activation of constitutive NOS, and in the present paper, we evaluated whether it could interfere with the expression of iNOS, which is activated by lipopolysaccharide (LPS), a major component of gram-negative bacteria cell walls. Melatonin nitric oxide synthase 2 Rattus norvegicus