Title : Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.

Pub. Date : 2009 Apr 28

PMID : 19207106






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, ADAM15-dependent processing of FGFR2iiib was inhibited by the hydroxamate-based metalloproteinase inhibitors marimastat, TAPI-2 and GM6001, and by 50 nM TIMP-3 (tissue inhibitor of metalloproteinases 3), but not by 100 nM TIMP-1, and only weakly by 100 nM TIMP-2. hydroxamate TIMP metallopeptidase inhibitor 1 Homo sapiens