Title : Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects.

Pub. Date : 2009

PMID : 19183864






3 Functional Relationships(s)
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Protein Name
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1 Although both arimoclomol and celastrol induced the expression of Hsp70, their effects on primary motoneurons in culture were significantly different. celastrol heat shock protein 1B Mus musculus
2 Immunostaining of celastrol-treated cultures for hsp70 and activated caspase-3 revealed that celastrol treatment activates both the heat shock response and the apoptotic cell death cascade. celastrol heat shock protein 1B Mus musculus
3 Immunostaining of celastrol-treated cultures for hsp70 and activated caspase-3 revealed that celastrol treatment activates both the heat shock response and the apoptotic cell death cascade. celastrol heat shock protein 1B Mus musculus