Protein Name | heat shock protein 1B |
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Organism | Mus musculus |
Gene ID | 15511 |
Gene Symbol | Hspa1b |
UniProt | P17879 (HS71B_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
419
Total Number of Articles : 539 |
Description |
heat shock protein 1B |
Gene Summary |
Enables protein folding chaperone. Involved in protein folding. Acts upstream of or within binding activity of sperm to zona pellucida; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; and response to heat. Located in cell body and mitochondrion. Part of zona pellucida receptor complex. Is expressed in early conceptus; embryo; and humerus. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; obesity; toxic shock syndrome; type 2 diabetes mellitus; and urinary tract infection. Orthologous to human HSPA1B (heat shock protein family A (Hsp70) member 1B). [provided by Alliance of Genome Resources, Apr 2022] |
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