Protein Name heat shock protein 1B
Organism Mus musculus
Gene ID 15511
Gene Symbol

Hspa1b

UniProt P17879 (HS71B_MOUSE)
Relationships Total Number of functionally related compound(s) : 419
Total Number of Articles : 539
Description

heat shock protein 1B

Gene Summary

Enables protein folding chaperone. Involved in protein folding. Acts upstream of or within binding activity of sperm to zona pellucida; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; and response to heat. Located in cell body and mitochondrion. Part of zona pellucida receptor complex. Is expressed in early conceptus; embryo; and humerus. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; obesity; toxic shock syndrome; type 2 diabetes mellitus; and urinary tract infection. Orthologous to human HSPA1B (heat shock protein family A (Hsp70) member 1B). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • heat shock 70 kDa protein 1B
  • 68 kDa heat shock protein
  • heat shock 70 kDa protein 1
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Properties