Title : Histamine N-methyltransferase 939A>G polymorphism affects mRNA stability in patients with acetylsalicylic acid-intolerant chronic urticaria.

Pub. Date : 2009 Feb

PMID : 19178400






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Histamine levels are regulated by histamine N-methyltransferase (HNMT). Histamine histamine N-methyltransferase Homo sapiens
2 Histamine levels are regulated by histamine N-methyltransferase (HNMT). Histamine histamine N-methyltransferase Homo sapiens
3 CONCLUSION: The HNMT 939A>G polymorphism lowers HNMT enzymatic activity by decreasing HNMT mRNA stability, which leads to an increase in the histamine level and contributes to the development of AICU. Histamine histamine N-methyltransferase Homo sapiens
4 CONCLUSION: The HNMT 939A>G polymorphism lowers HNMT enzymatic activity by decreasing HNMT mRNA stability, which leads to an increase in the histamine level and contributes to the development of AICU. Histamine histamine N-methyltransferase Homo sapiens
5 CONCLUSION: The HNMT 939A>G polymorphism lowers HNMT enzymatic activity by decreasing HNMT mRNA stability, which leads to an increase in the histamine level and contributes to the development of AICU. Histamine histamine N-methyltransferase Homo sapiens