Pub. Date : 2009 Mar
PMID : 19158217
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glycine decarboxylation through the glycine cleavage system (GCS) and glycine-serine transformation by serine hydroxymethyltransferase (SHMT) require pyridoxal 5"-phosphate (PLP; active form of vitamin B-6) as a coenzyme. | Glycine | serine hydroxymethyltransferase 1 | Homo sapiens |
| 2 | Glycine decarboxylation through the glycine cleavage system (GCS) and glycine-serine transformation by serine hydroxymethyltransferase (SHMT) require pyridoxal 5"-phosphate (PLP; active form of vitamin B-6) as a coenzyme. | Glycine | serine hydroxymethyltransferase 1 | Homo sapiens |
| 3 | Glycine decarboxylation through the glycine cleavage system (GCS) and glycine-serine transformation by serine hydroxymethyltransferase (SHMT) require pyridoxal 5"-phosphate (PLP; active form of vitamin B-6) as a coenzyme. | Glycine | serine hydroxymethyltransferase 1 | Homo sapiens |
| 4 | SHMT-mediated conversion of glycine to serine increased from 182 +/- 7 to 205 +/- 9 micromol x kg(-1) x h(-1) (P < 0.05), but serine production using a GCS-derived 1-carbon unit (93 +/- 9 vs. 91 +/- 6 micromol x kg(-1) x h(-1)) and glycine cleavage (163 +/- 11 vs. 151 +/- 8 micromol x kg(-1) x h(-1)) were not changed by vitamin B-6 restriction. | Glycine | serine hydroxymethyltransferase 1 | Homo sapiens |
| 5 | SHMT-mediated conversion of glycine to serine increased from 182 +/- 7 to 205 +/- 9 micromol x kg(-1) x h(-1) (P < 0.05), but serine production using a GCS-derived 1-carbon unit (93 +/- 9 vs. 91 +/- 6 micromol x kg(-1) x h(-1)) and glycine cleavage (163 +/- 11 vs. 151 +/- 8 micromol x kg(-1) x h(-1)) were not changed by vitamin B-6 restriction. | Glycine | serine hydroxymethyltransferase 1 | Homo sapiens |