Title : GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A receptors.

Pub. Date : 2009 Mar

PMID : 19141075






1 Functional Relationships(s)
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1 GDNF (10 ng/mL) enhanced (by approximately 13%) glutamate release from rat striatal nerve endings, an effect potentiated (up to approximately 30%) by the A(2A) receptor agonist CGS 21680 (10 nM) and prevented by the A(2A) receptor antagonist, SCH 58261 (50 nM). cysteinylglycine glial cell derived neurotrophic factor Rattus norvegicus