Title : Macrophages are not the source of injurious interleukin-18 in ischemic acute kidney injury in mice.

Pub. Date : 2009 Mar

PMID : 19129255






1 Functional Relationships(s)
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1 We previously reported in ischemic acute kidney injury (AKI) in mice that caspase-1-mediated production of interleukin-18 (IL-18) is pathogenic and that macrophage depletion by liposome-encapsulated clodronate (LEC) is protective. 4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE caspase 1 Mus musculus