Title : Radiosensitization by inhibiting STAT1 in renal cell carcinoma.

Pub. Date : 2009 Jan 1

PMID : 19100922






3 Functional Relationships(s)
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Protein Name
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1 STAT1 was reduced or inhibited by fludarabine and siRNA, respectively, and the effects on radiation-induced cell death were investigated using clonogenic assays. fludarabine signal transducer and activator of transcription 1 Homo sapiens
2 STAT1 expression was reduced by both fludarabine and siRNA, significantly increasing the radiosensitivity in both RCC cell lines. fludarabine signal transducer and activator of transcription 1 Homo sapiens
3 Radiosensitization in RCC cell lines was observed by a reduction or inhibition of STAT1 signaling, using fludarabine or siRNA. fludarabine signal transducer and activator of transcription 1 Homo sapiens