Pub. Date : 2009 Mar 2
PMID : 19084548
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UCP1 (p<0.01) and UCP3 (p<0.05) mRNA expressions were greater in risperidone-treated mice compared to controls, whereas, orexin mRNA expression was lower in risperidone-treated mice (p<0.01). | Risperidone | hypocretin | Mus musculus |
| 2 | These results suggest that risperidone-induced weight gain in mice is a consequence of increased energy intake and reduced activity, while the elevation in body temperature may be a result of thermogenic effect of food intake and elevated UCP1, UCP3, and a reduced hypothalamic orexin expression. | Risperidone | hypocretin | Mus musculus |