Title : Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?

Pub. Date : 2009 Apr

PMID : 19082994






5 Functional Relationships(s)
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1 Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected? Caffeine N-acetyltransferase 2 Homo sapiens
2 OBJECTIVES: Individual activities of N-acetyltransferase 2 (NAT2) and of xanthine oxidase (XO) can be assessed using ratios of urinary caffeine metabolites. Caffeine N-acetyltransferase 2 Homo sapiens
3 OBJECTIVES: Individual activities of N-acetyltransferase 2 (NAT2) and of xanthine oxidase (XO) can be assessed using ratios of urinary caffeine metabolites. Caffeine N-acetyltransferase 2 Homo sapiens
4 RESULTS: The NAT2 ratios were stable in the intervals 4-24 h after caffeine dosing. Caffeine N-acetyltransferase 2 Homo sapiens
5 CONCLUSIONS: Any sampling interval at least 4 h after caffeine dosing is suitable for NAT2 and XO activity assessments. Caffeine N-acetyltransferase 2 Homo sapiens