Title : Phospholipase Cgamma1 is required for metastasis development and progression.

Pub. Date : 2008 Dec 15

PMID : 19074886






1 Functional Relationships(s)
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1 In this study, we show that down-regulation of PLCgamma1 expression severely impairs activation of the small GTP-binding protein Rac and cell invasion in breast cancer cell lines and U87 in vitro. Guanosine Triphosphate phospholipase C gamma 1 Homo sapiens