Pub. Date : 2009 Apr
PMID : 19065636
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By using the nocodazole-induced Dami cell model, we found that 4E-BP1 and Thr421/Ser424 of ribosomal S6 kinase 1(S6K1) were phosphorylated mostly at M-phase in cytoplasm and oscillated in nocodazole-induced polyploid Dami cells, concomitant with increased expression of p27 and cyclin D3. | Nocodazole | ribosomal protein S6 kinase B1 | Homo sapiens |
| 2 | By using the nocodazole-induced Dami cell model, we found that 4E-BP1 and Thr421/Ser424 of ribosomal S6 kinase 1(S6K1) were phosphorylated mostly at M-phase in cytoplasm and oscillated in nocodazole-induced polyploid Dami cells, concomitant with increased expression of p27 and cyclin D3. | Nocodazole | ribosomal protein S6 kinase B1 | Homo sapiens |
| 3 | Moreover, overexpression of rapamycin-resistant form of S6K1 significantly reversed polyploidization of nocodazole-induced Dami cells. | Nocodazole | ribosomal protein S6 kinase B1 | Homo sapiens |